Careers

1. Sequence design of siRNA drugs on the existing platform of Saint Germain.

2. Based on the existing data of the company, further optimize the siRNA drug design platform through machine learning and algorithm optimization, improve the rationality of sequence design and the reliability of off target prediction, etc.

3. Perform data analysis of RNAseq and single cell seq to provide bioinformatics support for in vitro and in vivo efficacy and safety evaluations, including off target analysis.

4. Collaborate with the team to conduct research on drug targets and optimize chemical modifications.

5. Assist in establishing and maintaining a database.

6.Assist in writing and reviewing application documents, articles, patents, etc.

1. Doctoral degree or master's degree with at least two years of work experience; Background in bioinformatics or other related fields.

2. Familiar with RNA biology and oligonucleotide technology, with experience in siRNA drug discovery is preferred, and work experience in targeting, drug design, or chemical modification is preferred.

3. Familiar with bioinformatics data resources and analysis tools, with RNA and DNA analysis skills and experience.

4. Proficient in at least one commonly used scripting language (such as R Python Perl), able to independently write analysis programs using scripting languages, and have good programming habits.

5. Strong subjective initiative and teamwork spirit.

6.Willing to learn new knowledge and skills.

1. Assist in the early development of small nucleic acid drugs.

2. Responsible for experiments related to cell, molecular biology, and immunity.

3. Assist in the construction of the analysis platform, including off target evaluation, etc.

1. Molecular biology, cell biology, molecular immunology, bioengineering, or other related majors in the field of biomedicine.

2. At least 2 years of undergraduate education and 1 year of biology related experience with a master's degree.

3. Proficient in cell culture, transfection, PCR, protein expression analysis (Western blot, Elisa) and other technologies, with experience in molecular biology or immunology experiments, or experience in small nucleic acid drug development is preferred.

4. Proficient in using various office software, responsible and proactive in work, with a strong sense of responsibility, good communication skills, and a good team spirit.